Rosacea: An Introduction

Example 11 - Use of Epinephrine

An epinephrine solution (Epipen.RTM., trademark of Dey.RTM., L.P.) containing approximately 0.3 mg of epinephrine was placed in a glass container. The solution was placed onto a cotton tipped swab and then applied to approximately 4 cm.sup.2 of naso-facial skin displaying rosacea induced erythema. Within 5 minutes of application a mottled whitening of the skin was observed. No whitening was observed in skin outside of the application area. The whitening effect began to fade after approximately 30 minutes.


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